Here is how you can quickly replace or remove multiple characters/signs/symbol at once in any Microsoft Office product in any version.
While holding the CTRL key/button down press the H key/button down CTRL + H
You should see a smaller "Find and Replace" window.Click on the "Replace" tab in the menu of the new smaller "Find and Replace" window.
In that "Replace" tab in the very top "Find What" drop down section type the
characters/signs/symbol that you want to be removed or replaced.
In the "Replace With" section write/type the substitute characters/signs/symbol, if you want to substitute with nothing (empty space), leave the "Replace With" field/section empty.